ABSTRACT
One hundred and seventy four traffic policemen's pulmonary functions were measured via vitalograph. Abnormal pulmonary functions occurred in 44 persons (25.29%). There was restrictive lung in 30, small airway obstruction in 11 and large airway obstruction in 3.
Subject(s)
Humans , Lung Diseases/diagnosis , Male , Occupational Exposure/adverse effects , Police , Respiratory Function Tests , ThailandABSTRACT
In order to find out the correlation between preoperative pulmonary and nonpulmonary variables and the outcome of surgery, one hundred and five cases who had preoperative pulmonary evaluation were included in the study. Of 105 cases, 88 cases underwent surgery. The majority of the cases were old (62.5 +/- 9.63 yrs), with no chest symptoms and signs. The spirometric values in most cases were normal. Most of them were smokers, with the diagnosis of carcinoma of esophagus and underwent thoracoabdominal surgery. Postoperative pulmonary complication was found in 58 cases and mortality was encountered in 12 cases. FEV1, FEF 25-75 per cent and PFEF 25-75 per cent could discriminate survival from death. Duration of surgery (DS) and age factors could predict post-operative pulmonary complication. Only DS could predict prolonged hospital stay, when PFEF 25-75 per cent was coupled with DS, it could predict survival. It was concluded that multiple factors other than spirometric values were responsible for the surgical outcome. They should be taken into consideration for preoperative pulmonary evaluation.
Subject(s)
Adult , Aged , Evaluation Studies as Topic , Female , Humans , Lung Diseases/etiology , Male , Middle Aged , Postoperative Complications/prevention & control , Preoperative Care , Retrospective Studies , Spirometry , Treatment OutcomeABSTRACT
A double-blind, cross over, placebo controlled study was conducted to compare the response of lung function to metered doses inhaler of ipratropium bromide (IB, 40 micrograms, fenoterol hydrobromide (F), 100 micrograms, and a combination of the two (IBF). The drugs were administered on 4 consecutive days to 16 stable chronic airway obstructive patients (COPD), all of whom had shown minimal improvement after inhaling sympathomimetic drugs. Lung function response was measured for six hours after administration. All active medications caused greater improvement of FEV1 and FVC than the placebo did and none caused cardiovascular side effects. Improvement of FEV1 and FVC after IBF therapy was significantly better than after F at 1 hour and lasted up to six hour, whereas IBF was better than IB only after the third hour onwards. In addition, additive effects on FEV1 and FVC were seen in this period. IB caused greater response in FEV1 and FVC than F at both first and fifth hour. IB and IBF showed a rapid onset of action and had greater duration of action than F.